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Chapter 70 HIV Infection Sample Questions

1. The doctor of a 40-year-old patient, JPK calls because of recent high triglyceride level. JPK is currently receiving treatment for Human Immunodeficiency Virus (HIV) infection with regimen as follows:
Lamivudine (3TC) 300 mg once daily PO in the morning
Tenofovir DF 300 mg once daily PO in the morning
Lopinavir/Ritonavir 400/100 mg bid PO in the morning and at night
JPK’s other medical condition includes hypothyroidism for which he is taking Levothyroxine 25 mcg daily po. The doctor wants to know what likely caused hypertriglyceridemia. What will you tell him?

A. Drug interaction between Levothyroxine and Lamivudine.
B. Drug interaction between Levothyroxine and HIV.
C. Side effects of Lamivudine.
D. Side effects of Lopinavir/Ritonavir.

Answer

Ans: D

Tips: CPS. Except for atazanavir, all Protease inhibitors are associated with hyperlipidemia side effect.

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